Elevated levels of extracellular vesicles in progranulin‐deficient mice and FTD‐GRN Patients

OBJECTIVE: The goal of this study was to investigate the effect of progranulin insufficiency on extracellular vesicles (EVs), a heterogeneous population of vesicles that may contribute to progression of neurodegenerative disease. Loss‐of‐function mutations in progranulin (GRN) are a major cause of f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Ann Clin Transl Neurol
Main Authors: Arrant, Andrew E., Davis, Skylar E., Vollmer, Rachael M., Murchison, Charles F., Mobley, James A., Nana, Alissa L., Spina, Salvatore, Grinberg, Lea T., Karydas, Anna M., Miller, Bruce L., Seeley, William W., Roberson, Erik D.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732244/
https://ncbi.nlm.nih.gov/pubmed/33197149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51242
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