A mathematical model of ctDNA shedding predicts tumor detection size

Early cancer detection aims to find tumors before they progress to an incurable stage. To determine the potential of circulating tumor DNA (ctDNA) for cancer detection, we developed a mathematical model of tumor evolution and ctDNA shedding to predict the size at which tumors become detectable. From...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Avanzini, Stefano, Kurtz, David M., Chabon, Jacob J., Moding, Everett J., Hori, Sharon Seiko, Gambhir, Sanjiv Sam, Alizadeh, Ash A., Diehn, Maximilian, Reiter, Johannes G.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732186/
https://ncbi.nlm.nih.gov/pubmed/33310847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc4308
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