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A mathematical model of ctDNA shedding predicts tumor detection size

Early cancer detection aims to find tumors before they progress to an incurable stage. To determine the potential of circulating tumor DNA (ctDNA) for cancer detection, we developed a mathematical model of tumor evolution and ctDNA shedding to predict the size at which tumors become detectable. From...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Avanzini, Stefano, Kurtz, David M., Chabon, Jacob J., Moding, Everett J., Hori, Sharon Seiko, Gambhir, Sanjiv Sam, Alizadeh, Ash A., Diehn, Maximilian, Reiter, Johannes G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732186/
https://ncbi.nlm.nih.gov/pubmed/33310847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc4308
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