Region-specific and dose-specific effects of chronic haloperidol exposure on [(3)H]-flumazenil and [(3)H]-Ro15-4513 GABA(A) receptor binding sites in the rat brain

Postmortem studies suggest that schizophrenia is associated with abnormal expression of specific GABA(A) receptor (GABA(A)R) α subunits, including α5GABA(A)R. Positron emission tomography (PET) measures of GABA(A)R availability in schizophrenia, however, have not revealed consistent alterations in v...

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Detalhes bibliográficos
Publicado no:Eur Neuropsychopharmacol
Main Authors: Peris-Yague, Alba, Kiemes, Amanda, Cash, Diana, Cotel, Marie-Caroline, Singh, Nisha, Vernon, Anthony C., Modinos, Gemma
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731940/
https://ncbi.nlm.nih.gov/pubmed/33153853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2020.10.004
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