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Quantification of [(11)C]Ro15-4513 GABA(A)α5 specific binding and regional selectivity in humans

[(11)C]Ro15-4513 has been introduced as a positron emission tomography radioligand to image the GABA(A)α5 receptor subtype thought to be important in learning, memory and addiction. However, the in vivo selectivity of the ligand remains unknown and a full assessment of different analysis approaches...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Myers, Jim FM, Comley, Robert A, Gunn, Roger N
Format: Artigo
Language:Inglês
Published: SAGE Publications 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464707/
https://ncbi.nlm.nih.gov/pubmed/27466376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16661339
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