TGF-β Induced CTGF Expression in Human Lung Epithelial Cells through ERK, ADAM17, RSK1, and C/EBPβ Pathways

Background: Lung epithelial cells play critical roles in idiopathic pulmonary fibrosis. Methods: In the present study, we investigated whether transforming growth factor-β (TGF-β)-induced expression of connective tissue growth factor (CTGF) was regulated by the extracellular signal-regulated kinase...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Ou, Shu-Ching, Bai, Kuan-Jen, Cheng, Wun-Hao, Chen, Jing-Yun, Lin, Chien-Huang, Wen, Heng-Ching, Chen, Bing-Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731197/
https://ncbi.nlm.nih.gov/pubmed/33260349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239084
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