Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

Due to its antiangiogenic and anti-immunomodulatory activity, thalidomide continues to be of clinical interest despite its teratogenic actions, and efforts to synthesize safer, clinically active thalidomide analogs are continually underway. In this study, a cohort of 27 chemically diverse thalidomid...

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Publicado en:Molecules
Autores principales: Peach, Megan L., Beedie, Shaunna L., Chau, Cindy H., Collins, Matthew K., Markolovic, Suzana, Luo, Weiming, Tweedie, David, Steinebach, Christian, Greig, Nigel H., Gütschow, Michael, Vargesson, Neil, Nicklaus, Marc C., Figg, William D.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730988/
https://ncbi.nlm.nih.gov/pubmed/33276504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235683
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