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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

Due to its antiangiogenic and anti-immunomodulatory activity, thalidomide continues to be of clinical interest despite its teratogenic actions, and efforts to synthesize safer, clinically active thalidomide analogs are continually underway. In this study, a cohort of 27 chemically diverse thalidomid...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Peach, Megan L., Beedie, Shaunna L., Chau, Cindy H., Collins, Matthew K., Markolovic, Suzana, Luo, Weiming, Tweedie, David, Steinebach, Christian, Greig, Nigel H., Gütschow, Michael, Vargesson, Neil, Nicklaus, Marc C., Figg, William D.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730988/
https://ncbi.nlm.nih.gov/pubmed/33276504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235683
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