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The Effect of Methylmalonic Acid Treatment on Human Neuronal Cell Coenzyme Q(10) Status and Mitochondrial Function

Methylmalonic acidemia is an inborn metabolic disease of propionate catabolism, biochemically characterized by accumulation of methylmalonic acid (MMA) to millimolar concentrations in tissues and body fluids. However, MMA’s role in the pathophysiology of the disorder and its status as a “toxic inter...

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Pubblicato in:Int J Mol Sci
Autori principali: Proctor, Emma C., Turton, Nadia, Boan, Elle Jo, Bennett, Emily, Philips, Suzannah, Heaton, Robert A., Hargreaves, Iain P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730949/
https://ncbi.nlm.nih.gov/pubmed/33266298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239137
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