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The Effect of Methylmalonic Acid Treatment on Human Neuronal Cell Coenzyme Q(10) Status and Mitochondrial Function

Methylmalonic acidemia is an inborn metabolic disease of propionate catabolism, biochemically characterized by accumulation of methylmalonic acid (MMA) to millimolar concentrations in tissues and body fluids. However, MMA’s role in the pathophysiology of the disorder and its status as a “toxic inter...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Proctor, Emma C., Turton, Nadia, Boan, Elle Jo, Bennett, Emily, Philips, Suzannah, Heaton, Robert A., Hargreaves, Iain P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730949/
https://ncbi.nlm.nih.gov/pubmed/33266298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239137
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