Checkpoint Kinase 1 Pharmacological Inhibition Synergizes with DNA-Damaging Agents and Overcomes Platinum Resistance in Basal-Like Breast Cancer

Basal-like breast cancer is an incurable disease with limited therapeutic options, mainly due to the frequent development of anti-cancer drug resistance. Therefore, identification of druggable targets to improve current therapies and overcome these resistances is a major goal. Targeting DNA repair m...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Nieto-Jimenez, Cristina, Alcaraz-Sanabria, Ana, Martinez-Canales, Sandra, Corrales-Sanchez, Veronica, Montero, Juan Carlos, Burgos, Miguel, Nuncia-Cantarero, Miriam, Pandiella, Atanasio, Galan-Moya, Eva M., Ocaña, Alberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730833/
https://ncbi.nlm.nih.gov/pubmed/33261142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239034
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