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Designing next generation recombinant protein expression platforms by modulating the cellular stress response in Escherichia coli

BACKGROUND: A cellular stress response (CSR) is triggered upon recombinant protein synthesis which acts as a global feedback regulator of protein expression. To remove this key regulatory bottleneck, we had previously proposed that genes that are up-regulated post induction could be part of the sign...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Guleria, Richa, Jain, Priyanka, Verma, Madhulika, Mukherjee, Krishna J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730785/
https://ncbi.nlm.nih.gov/pubmed/33308214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01488-w
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