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Evaluating coverage bias in next-generation sequencing of Escherichia coli
Whole-genome sequencing is essential to many facets of infectious disease research. However, technical limitations such as bias in coverage and tagmentation, and difficulties characterising genomic regions with extreme GC content have created significant obstacles in its use. Illumina has claimed th...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8224930/ https://ncbi.nlm.nih.gov/pubmed/34166413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0253440 |
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