Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro

Sepsis is a major cause of mortality in critically ill patients and associated with cardiac dysfunction, a complication linked to immunological and metabolic aberrations. Cardiac neutrophil infiltration and subsequent release of myeloperoxidase (MPO) leads to the formation of the oxidant hypochlorou...

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Udgivet i:Int J Mol Sci
Main Authors: Prasch, Jürgen, Bernhart, Eva, Reicher, Helga, Kollroser, Manfred, Rechberger, Gerald N., Koyani, Chintan N., Trummer, Christopher, Rech, Lavinia, Rainer, Peter P., Hammer, Astrid, Malle, Ernst, Sattler, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730634/
https://ncbi.nlm.nih.gov/pubmed/33287422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239235
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