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Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids
Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na(+)/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV cell-e...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7729925/ https://ncbi.nlm.nih.gov/pubmed/33303817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78618-2 |
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