Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na(+)/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV cell-e...

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Publicado no:Sci Rep
Main Authors: Kirstgen, Michael, Lowjaga, Kira Alessandra Alicia Theresa, Müller, Simon Franz, Goldmann, Nora, Lehmann, Felix, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Glebe, Dieter, Geyer, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729925/
https://ncbi.nlm.nih.gov/pubmed/33303817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78618-2
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