Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells

Umbilical cord blood (UCB) has been established as an alternative source for hematopoietic stem/progenitor cells (HSPC) for cell and gene therapies. Limited cell yields of UCB units have been tackled with the development of cytokine-based ex vivo expansion platforms. To improve the effectiveness of...

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Publicat a:Front Bioeng Biotechnol
Autors principals: Branco, André, Bucar, Sara, Moura-Sampaio, Jorge, Lilaia, Carla, Cabral, Joaquim M. S., Fernandes-Platzgummer, Ana, Lobato da Silva, Cláudia
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Bioengineering and Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729524/
https://ncbi.nlm.nih.gov/pubmed/33330414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.573282
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