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Wnt3a nanodisks promote ex vivo expansion of hematopoietic stem and progenitor cells
BACKGROUND: Wnt proteins modulate development, stem cell fate and cancer through interactions with cell surface receptors. Wnts are cysteine-rich, glycosylated, lipid modified, two domain proteins that are prone to aggregation. The culprit responsible for this behavior is a covalently bound palmitol...
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| Publicado no: | J Nanobiotechnology |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4995738/ https://ncbi.nlm.nih.gov/pubmed/27553039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-016-0218-5 |
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