A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion

The main limitations of hematopoietic cord blood (CB) transplantation, viz, low cell dosage and delayed reconstitution, can be overcome by ex vivo expansion. CB expansion under conventional culture causes rapid cell differentiation and depletion of hematopoietic stem and progenitor cells (HSPCs) res...

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Bibliografski detalji
Izdano u:Stem Cells Dev
Glavni autori: Tarunina, Marina, Hernandez, Diana, Kronsteiner-Dobramysl, Barbara, Pratt, Philip, Watson, Thomas, Hua, Peng, Gullo, Francesca, van der Garde, Mark, Zhang, Youyi, Hook, Lilian, Choo, Yen, Watt, Suzanne M.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2016
Teme:
Original Research Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105341/
https://ncbi.nlm.nih.gov/pubmed/27554619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0216
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