A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion

The main limitations of hematopoietic cord blood (CB) transplantation, viz, low cell dosage and delayed reconstitution, can be overcome by ex vivo expansion. CB expansion under conventional culture causes rapid cell differentiation and depletion of hematopoietic stem and progenitor cells (HSPCs) res...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Tarunina, Marina, Hernandez, Diana, Kronsteiner-Dobramysl, Barbara, Pratt, Philip, Watson, Thomas, Hua, Peng, Gullo, Francesca, van der Garde, Mark, Zhang, Youyi, Hook, Lilian, Choo, Yen, Watt, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105341/
https://ncbi.nlm.nih.gov/pubmed/27554619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0216
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