A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion

The main limitations of hematopoietic cord blood (CB) transplantation, viz, low cell dosage and delayed reconstitution, can be overcome by ex vivo expansion. CB expansion under conventional culture causes rapid cell differentiation and depletion of hematopoietic stem and progenitor cells (HSPCs) res...

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Bibliografiske detaljer
Udgivet i:Stem Cells Dev
Main Authors: Tarunina, Marina, Hernandez, Diana, Kronsteiner-Dobramysl, Barbara, Pratt, Philip, Watson, Thomas, Hua, Peng, Gullo, Francesca, van der Garde, Mark, Zhang, Youyi, Hook, Lilian, Choo, Yen, Watt, Suzanne M.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2016
Fag:
Original Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105341/
https://ncbi.nlm.nih.gov/pubmed/27554619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0216
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