RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat

MicroRNAs are small (~ 22nt long) noncoding RNAs (ncRNAs) that regulate gene expression at the post-transcriptional level. Over 2000 microRNAs have been described in humans and many are implicated in human pathologies including tissue fibrosis. Hepatic stellate cells (HSC) are the major cellular con...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Sabater, Laura, Locatelli, Luigi, Oakley, Fiona, Hardy, Timothy, French, Jeremy, Robinson, Stuart M., Sen, Gourab, Mann, D. A., Mann, Jelena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728773/
https://ncbi.nlm.nih.gov/pubmed/33303921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78776-3
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