Structure-activity relationships study of isothiocyanates for H(2)S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent

INTRODUCTION: The gasotransmitter hydrogen sulphide (H(2)S), an endogenous ubiquitous signalling molecule, is known for its beneficial effects on different mammalian systems. H(2)S exhibits cardioprotective activity against ischemia/reperfusion (I/R) or hypoxic injury. METHODS: A library of forty-fi...

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Udgivet i:J Adv Res
Main Authors: Citi, Valentina, Corvino, Angela, Fiorino, Ferdinando, Frecentese, Francesco, Magli, Elisa, Perissutti, Elisa, Santagada, Vincenzo, Brogi, Simone, Flori, Lorenzo, Gorica, Era, Testai, Lara, Martelli, Alma, Calderone, Vincenzo, Caliendo, Giuseppe, Severino, Beatrice
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728584/
https://ncbi.nlm.nih.gov/pubmed/33318865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2020.02.017
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