Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins

The HIV-1 nucleocapsid (NC) protein represents an excellent molecular target for the development of antiretrovirals by virtue of its well-characterized chaperone activities, which play pivotal roles in essential steps of the viral life cycle. Our ongoing search for candidates able to impair NC bindi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Bioconjug Chem
Hlavní autoři: Sosic, Alice, Saccone, Irene, Carraro, Caterina, Kenderdine, Thomas, Gamba, Elia, Caliendo, Giuseppe, Corvino, Angela, Di Vaio, Paola, Fiorino, Ferdinando, Magli, Elisa, Perissutti, Elisa, Santagada, Vincenzo, Severino, Beatrice, Spada, Valentina, Fabris, Dan, Frecentese, Francesco, Gatto, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175782/
https://ncbi.nlm.nih.gov/pubmed/29791798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00104
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky