CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

cGAS/DncV-like nucleotidyltransferase (CD-NTase) enzymes are immune sensors that synthesize nucleotide second messengers and initiate antiviral responses in bacterial and animal cells. Here, we discover Enterobacter cloacae CD-NTase-associated protein 4 (Cap4) as a founding member of a diverse famil...

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Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Lowey, Brianna, Whiteley, Aaron T., Keszei, Alexander F.A., Morehouse, Benjamin R., Mathews, Ian T., Antine, Sadie P., Cabrera, Victor J., Kashin, Dmitry, Niemann, Percy, Jain, Mohit, Schwede, Frank, Mekalanos, John J., Shao, Sichen, Lee, Amy S.Y., Kranzusch, Philip J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728545/
https://ncbi.nlm.nih.gov/pubmed/32544385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.019
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