Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...

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Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Qin, Xin, Jiang, Qing, Nagano, Kenichi, Moriishi, Takeshi, Miyazaki, Toshihiro, Komori, Hisato, Ito, Kosei, von der Mark, Klaus, Sakane, Chiharu, Kaneko, Hitomi, Komori, Toshihisa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728394/
https://ncbi.nlm.nih.gov/pubmed/33253203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009169
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