Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Qin, Xin, Jiang, Qing, Nagano, Kenichi, Moriishi, Takeshi, Miyazaki, Toshihiro, Komori, Hisato, Ito, Kosei, von der Mark, Klaus, Sakane, Chiharu, Kaneko, Hitomi, Komori, Toshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728394/
https://ncbi.nlm.nih.gov/pubmed/33253203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009169
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