Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...

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Vydáno v:PLoS Genet
Hlavní autoři: Qin, Xin, Jiang, Qing, Nagano, Kenichi, Moriishi, Takeshi, Miyazaki, Toshihiro, Komori, Hisato, Ito, Kosei, von der Mark, Klaus, Sakane, Chiharu, Kaneko, Hitomi, Komori, Toshihisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728394/
https://ncbi.nlm.nih.gov/pubmed/33253203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009169
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