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Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts
Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7728394/ https://ncbi.nlm.nih.gov/pubmed/33253203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009169 |
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