Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Qin, Xin, Jiang, Qing, Nagano, Kenichi, Moriishi, Takeshi, Miyazaki, Toshihiro, Komori, Hisato, Ito, Kosei, von der Mark, Klaus, Sakane, Chiharu, Kaneko, Hitomi, Komori, Toshihisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728394/
https://ncbi.nlm.nih.gov/pubmed/33253203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009169
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