Human splice factors contribute to latent HIV infection in primary cell models and blood CD4(+) T cells from ART-treated individuals

It is unclear what mechanisms govern latent HIV infection in vivo or in primary cell models. To investigate these questions, we compared the HIV and cellular transcription profile in three primary cell models and peripheral CD4(+) T cells from HIV-infected ART-suppressed individuals using RT-ddPCR a...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Moron-Lopez, Sara, Telwatte, Sushama, Sarabia, Indra, Battivelli, Emilie, Montano, Mauricio, Macedo, Amanda B., Aran, Dvir, Butte, Atul J., Jones, R. Brad, Bosque, Alberto, Verdin, Eric, Greene, Warner C., Wong, Joseph K., Yukl, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728277/
https://ncbi.nlm.nih.gov/pubmed/33253324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009060
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