Human splice factors contribute to latent HIV infection in primary cell models and blood CD4(+) T cells from ART-treated individuals

It is unclear what mechanisms govern latent HIV infection in vivo or in primary cell models. To investigate these questions, we compared the HIV and cellular transcription profile in three primary cell models and peripheral CD4(+) T cells from HIV-infected ART-suppressed individuals using RT-ddPCR a...

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發表在:PLoS Pathog
Main Authors: Moron-Lopez, Sara, Telwatte, Sushama, Sarabia, Indra, Battivelli, Emilie, Montano, Mauricio, Macedo, Amanda B., Aran, Dvir, Butte, Atul J., Jones, R. Brad, Bosque, Alberto, Verdin, Eric, Greene, Warner C., Wong, Joseph K., Yukl, Steven A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728277/
https://ncbi.nlm.nih.gov/pubmed/33253324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009060
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