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Remote homology search with hidden Potts models

Most methods for biological sequence homology search and alignment work with primary sequence alone, neglecting higher-order correlations. Recently, statistical physics models called Potts models have been used to infer all-by-all pairwise correlations between sites in deep multiple sequence alignme...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Wilburn, Grey W., Eddy, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728182/
https://ncbi.nlm.nih.gov/pubmed/33253143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008085
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