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Lysosome-targeting chimaeras for degradation of extracellular proteins
The majority of therapies that target individual proteins rely on specific activitymodulating interactions with the target protein–for example, enzyme inhibition or ligand blocking. However, several major classes of therapeutically relevant proteins have unknown or inaccessible activity profiles and...
Gorde:
| Argitaratua izan da: | Nature |
|---|---|
| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7727926/ https://ncbi.nlm.nih.gov/pubmed/32728216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2545-9 |
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