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Induced oligomerization targets Golgi proteins for degradation in lysosomes
Manganese protects cells against forms of Shiga toxin by down-regulating the cycling Golgi protein GPP130. Down-regulation occurs when Mn binding causes GPP130 to oligomerize and traffic to lysosomes. To determine how GPP130 is redirected to lysosomes, we tested the role of GGA1 and clathrin, which...
Sparad:
| I publikationen: | Mol Biol Cell |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The American Society for Cell Biology
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666137/ https://ncbi.nlm.nih.gov/pubmed/26446839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0207 |
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