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Induced oligomerization targets Golgi proteins for degradation in lysosomes
Manganese protects cells against forms of Shiga toxin by down-regulating the cycling Golgi protein GPP130. Down-regulation occurs when Mn binding causes GPP130 to oligomerize and traffic to lysosomes. To determine how GPP130 is redirected to lysosomes, we tested the role of GGA1 and clathrin, which...
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| Pubblicato in: | Mol Biol Cell |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666137/ https://ncbi.nlm.nih.gov/pubmed/26446839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0207 |
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