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Induced oligomerization targets Golgi proteins for degradation in lysosomes
Manganese protects cells against forms of Shiga toxin by down-regulating the cycling Golgi protein GPP130. Down-regulation occurs when Mn binding causes GPP130 to oligomerize and traffic to lysosomes. To determine how GPP130 is redirected to lysosomes, we tested the role of GGA1 and clathrin, which...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Biol Cell |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The American Society for Cell Biology
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666137/ https://ncbi.nlm.nih.gov/pubmed/26446839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0207 |
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