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Rapamycin Eyedrops Increased CD4(+)Foxp3(+) Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface
Dry eye disease (DED), one of the most prevalent conditions among the elderly, is a chronic inflammatory disorder that disrupts tear film stability and causes ocular surface damage. Aged C57BL/6J mice spontaneously develop DED. Rapamycin is a potent immunosuppressant that prolongs the lifespan of se...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7727717/ https://ncbi.nlm.nih.gov/pubmed/33255287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238890 |
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