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Bullet points to evaluate the performance of the middle-down proteomics workflow for histone modification analysis
Middle-down proteomics has emerged as the method of choice to study combinatorial histone post translational modifications (PTMs). In the common bottom-up workflow, histones are digested into relatively short peptides (4–20 aa), separated using reversed-phase chromatography and analyzed using typica...
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| Udgivet i: | Methods |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7727281/ https://ncbi.nlm.nih.gov/pubmed/32070774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2020.01.013 |
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