Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code

Abstract Background Middle-down mass spectrometry (MS), i.e., analysis of long (~50–60 aa) polypeptides, has become the method with the highest throughput and accuracy for the characterization of combinatorial histone posttranslational modifications (PTMs). The discovery of histone readers with mult...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Simone Sidoli, Congcong Lu, Mariel Coradin, Xiaoshi Wang, Kelly R. Karch, Chrystian Ruminowicz, Benjamin A. Garcia
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-07-01
Colecção:Epigenetics & Chromatin
Assuntos:
Epigenetics
Histones
Mass spectrometry
Methylation
Middle-down
Posttranslational modifications
Acesso em linha:http://link.springer.com/article/10.1186/s13072-017-0139-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados