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Low resolution data-independent acquisition in an LTQ-Orbitrap allows for simplified and fully untargeted analysis of histone modifications
Label-free peptide quantification in LC-MS proteomics analyses is complicated by the presence of isobaric co-eluting peptides, as they generate the same extracted ion chromatogram corresponding to the sum of their intensities. Histone proteins are especially prone to this, as they are heavily modifi...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811372/ https://ncbi.nlm.nih.gov/pubmed/26505526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b03009 |
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