Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

OBJECTIVES: Systemic sclerosis (SSc) is characterised by tissue fibrosis of the major organs of the body including the skin, lungs and heart. We have previously reported that the lncRNA HOTAIR plays a central role in the activation of SSc myofibroblasts, the key cellular elements of fibrosis. HOTAIR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Wasson, Christopher W., Ross, Rebecca L., Wells, Rebecca, Corinaldesi, Clarissa, Georgiou, Ioanna Ch., Riobo-Del Galdo, Natalia A., Del Galdo, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726858/
https://ncbi.nlm.nih.gov/pubmed/33303026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02376-9
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge