Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist

Por Macleod, Tom, Doble, Rosella, McGonagle, Dennis, Wasson, Christopher W., Alase, Adewonuola, Stacey, Martin, Wittmann, Miriam
Publicado no Sci Rep (2016)

Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5

Por Wetherill, Laura F., Wasson, Christopher W., Swinscoe, Gemma, Kealy, David, Foster, Richard, Griffin, Stephen, Macdonald, Andrew
Publicado no Antiviral Res (2018)

Human Papillomavirus E7 Oncoprotein Increases Production of the Anti-Inflammatory Interleukin-18 Binding Protein in Keratinocytes

Por Richards, Kathryn H., Doble, Rosella, Wasson, Christopher W., Haider, Mohammed, Blair, G. Eric, Wittmann, Miriam, Macdonald, Andrew
Publicado em 2014

The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes

Por Richards, Kathryn H., Wasson, Christopher W., Watherston, Oliver, Doble, Rosella, Eric Blair, G., Wittmann, Miriam, Macdonald, Andrew
Publicado no Sci Rep (2015)

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus lif...

Por Wasson, Christopher W., Morgan, Ethan L., Müller, Marietta, Ross, Rebecca L., Hartley, Margaret, Roberts, Sally, Macdonald, Andrew
Publicado no Oncotarget (2017)

YIP1 family member 4 (YIPF4) is a novel cellular binding partner of the papillomavirus E5 proteins

Por Müller, Marietta, Wasson, Christopher W., Bhatia, Ramya, Boxall, Sally, Millan, David, Goh, Grace Y.S., Haas, Jürgen, Stonehouse, Nicola J., Macdonald, Andrew
Publicado no Sci Rep (2015)

Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade

Por Panou, Margarita-Maria, Antoni, Michelle, Morgan, Ethan L., Loundras, Eleni-Anna, Wasson, Christopher W., Welberry-Smith, Matthew, Mankouri, Jamel, Macdonald, Andrew
Publicado no Antiviral Res (2020)

Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

Por Wasson, Christopher W., Ross, Rebecca L., Wells, Rebecca, Corinaldesi, Clarissa, Georgiou, Ioanna Ch., Riobo-Del Galdo, Natalia A., Del Galdo, Francesco
Publicado no Arthritis Res Ther (2020)

Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH

Por Wasson, Christopher W, Abignano, Giuseppina, Hermes, Heidi, Malaab, Maya, Ross, Rebecca L, Jimenez, Sergio A, Chang, Howard Y, Feghali-Bostwick, Carol A, del Galdo, Francesco
Publicado no Ann Rheum Dis (2020)

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

Por Stakaitytė, Gabrielė, Nwogu, Nnenna, Dobson, Samuel J., Knight, Laura M., Wasson, Christopher W., Salguero, Francisco J., Blackbourn, David J., Blair, G. Eric, Mankouri, Jamel, Macdonald, Andrew, Whitehouse, Adrian
Publicado no J Virol (2018)

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

Por Morgan, Ethan L., Patterson, Molly R., Ryder, Emma L., Lee, Siu Yi, Wasson, Christopher W., Harper, Katherine L., Li, Yigen, Griffin, Stephen, Blair, G. Eric, Whitehouse, Adrian, Macdonald, Andrew
Publicado no PLoS Pathog (2020)

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

Por Morgan, Ethan L., Wasson, Christopher W., Hanson, Lucy, Kealy, David, Pentland, Ieisha, McGuire, Victoria, Scarpini, Cinzia, Coleman, Nicholas, Arthur, J. Simon C., Parish, Joanna L., Roberts, Sally, Macdonald, Andrew
Publicado no PLoS Pathog (2018)