The Arabidopsis thaliana Poly(ADP-Ribose) Polymerases 1 and 2 Modify DNA by ADP-Ribosylating Terminal Phosphate Residues

Proteins from the poly(ADP-ribose) polymerase (PARP) family, such as PARP1 and PARP2, use NAD(+) as a substrate to catalyze the synthesis of polymeric chains consisting of ADP-ribose units covalently attached to an acceptor molecule. PARP1 and PARP2 are viewed as DNA damage sensors that, upon bindin...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Taipakova, Sabira, Kuanbay, Aigerim, Saint-Pierre, Christine, Gasparutto, Didier, Baiken, Yeldar, Groisman, Regina, Ishchenko, Alexander A., Saparbaev, Murat, Bissenbaev, Amangeldy K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726343/
https://ncbi.nlm.nih.gov/pubmed/33324653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.606596
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