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EB1 directly regulates APC-mediated actin nucleation

EB1 was discovered 25 years ago as a binding partner of the tumor suppressor Adenomatous Polyposis Coli (APC) [1]; however, the significance of EB1-APC interactions has remained poorly understood. EB1 functions at the center of a network of microtubule end-tracking proteins (+TIPs) [2–5], and APC bi...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Juanes, Maria Angeles, Fees, Colby, Hoeprich, Gregory J., Jaiswal, Richa, Goode, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726095/
https://ncbi.nlm.nih.gov/pubmed/33007249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.08.094
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