Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover

Cell motility depends on tight coordination between the microtubule (MT) and actin cytoskeletons, but the mechanisms underlying this MT–actin cross talk have remained poorly understood. Here, we show that the tumor suppressor protein adenomatous polyposis coli (APC), which is a known MT-associated p...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Juanes, M. Angeles, Bouguenina, Habib, Eskin, Julian A., Jaiswal, Richa, Badache, Ali, Goode, Bruce L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584174/
https://ncbi.nlm.nih.gov/pubmed/28663347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702007
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