The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Focal adhesion (FA) turnover depends on microtubules and actin. Microtubule ends are captured at FAs, where they induce rapid FA disassembly. However, actin’s roles are less clear. Here, we use polarization-resolved microscopy, FRAP, live cell imaging, and a mutant of Adenomatous polyposis coli (APC...

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Vydáno v:J Cell Biol
Hlavní autoři: Juanes, M. Angeles, Isnardon, Daniel, Badache, Ali, Brasselet, Sophie, Mavrakis, Manos, Goode, Bruce L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://ncbi.nlm.nih.gov/pubmed/31471457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904165
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