The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Focal adhesion (FA) turnover depends on microtubules and actin. Microtubule ends are captured at FAs, where they induce rapid FA disassembly. However, actin’s roles are less clear. Here, we use polarization-resolved microscopy, FRAP, live cell imaging, and a mutant of Adenomatous polyposis coli (APC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Juanes, M. Angeles, Isnardon, Daniel, Badache, Ali, Brasselet, Sophie, Mavrakis, Manos, Goode, Bruce L.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://ncbi.nlm.nih.gov/pubmed/31471457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904165
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