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The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Focal adhesion (FA) turnover depends on microtubules and actin. Microtubule ends are captured at FAs, where they induce rapid FA disassembly. However, actin’s roles are less clear. Here, we use polarization-resolved microscopy, FRAP, live cell imaging, and a mutant of Adenomatous polyposis coli (APC...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Juanes, M. Angeles, Isnardon, Daniel, Badache, Ali, Brasselet, Sophie, Mavrakis, Manos, Goode, Bruce L.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://ncbi.nlm.nih.gov/pubmed/31471457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904165
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