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The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

Focal adhesion (FA) turnover depends on microtubules and actin. Microtubule ends are captured at FAs, where they induce rapid FA disassembly. However, actin’s roles are less clear. Here, we use polarization-resolved microscopy, FRAP, live cell imaging, and a mutant of Adenomatous polyposis coli (APC...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Juanes, M. Angeles, Isnardon, Daniel, Badache, Ali, Brasselet, Sophie, Mavrakis, Manos, Goode, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781439/
https://ncbi.nlm.nih.gov/pubmed/31471457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904165
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