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Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models
Metabolic syndrome, a condition involving obesity and hypertension, increases the risk of aging-associated diseases such as age-related macular degeneration (AMD). Here, we demonstrated that high-fat diet (HFD)-fed mice accumulated oxidized low-density lipoprotein (ox-LDL) in macrophages through the...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Commun Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725839/ https://ncbi.nlm.nih.gov/pubmed/33299105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01483-2 |
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