Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium

Mitochondria participate in various metabolic pathways, and their dysregulation results in multiple disorders, including aging-related diseases. However, the metabolic changes and mechanisms of mitochondrial disorders are not fully understood. Here, we found that induced pluripotent stem cells (iPSC...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Homma, Kohei, Toda, Eriko, Osada, Hideto, Nagai, Norihiro, Era, Takumi, Tsubota, Kazuo, Okano, Hideyuki, Ozawa, Yoko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944050/
https://ncbi.nlm.nih.gov/pubmed/33706170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101921
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