Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity

Ferroptosis is a recently discovered iron-dependent form of oxidative programmed cell death distinct from caspase-dependent apoptosis. In this study, we investigated the effect of ferroptosis in neomycin-induced hair cell loss by using selective ferroptosis inhibitor liproxstatin-1 (Lip-1). Cell via...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Zheng, Zhiwei, Tang, Dongmei, Zhao, Liping, Li, Wen, Han, Jinghong, Hu, Bing, Nie, Guohui, He, Yingzi
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725559/
https://ncbi.nlm.nih.gov/pubmed/33343803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1782659
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