Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells

Aging, noise, and ototoxic drug-induced hair cell (HC) loss are the major causes of sensorineural hearing loss. Aminoglycoside antibiotics are commonly used in the clinic, but these often have ototoxic side effects due to the accumulation of oxygen-free radicals and the subsequent induction of HC ap...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Gao, Song, Cheng, Cheng, Wang, Maohua, Jiang, Pei, Zhang, Liyan, Wang, Ya, Wu, Huihui, Zeng, Xuanfu, Wang, Hui, Gao, Xia, Ma, Yongming, Chai, Renjie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025583/
https://ncbi.nlm.nih.gov/pubmed/32116554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00590
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