Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells

Aging, noise, and ototoxic drug-induced hair cell (HC) loss are the major causes of sensorineural hearing loss. Aminoglycoside antibiotics are commonly used in the clinic, but these often have ototoxic side effects due to the accumulation of oxygen-free radicals and the subsequent induction of HC ap...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Gao, Song, Cheng, Cheng, Wang, Maohua, Jiang, Pei, Zhang, Liyan, Wang, Ya, Wu, Huihui, Zeng, Xuanfu, Wang, Hui, Gao, Xia, Ma, Yongming, Chai, Renjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cellular Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025583/
https://ncbi.nlm.nih.gov/pubmed/32116554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00590
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