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Population variability in the generation and selection of T-cell repertoires
The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically stochastic steps: random receptor generation by VDJ recombination, and selection based on the recognition of random self-peptides presented on the major histocompatibility complex. These processes le...
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| Udgivet i: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725366/ https://ncbi.nlm.nih.gov/pubmed/33296360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008394 |
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